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Product Name: ABT-378 (Lopinavir) | HIV-1 protease inhibitor
Product Description: Lopinavir (ABT-378), designed in response to Val82 mutant strains of HIV [1], is a potent inhibitor of HIV protease with Ki of 1.3-3.6 pM. Lopinavir inhibits replication of HIV-1 with an EC50 of 6-17 nM. [2]Ritonavir was found to inhibit the metabolism ofMedchemexpress.com
Chemical Formula: C37H48N4O5
Molecular Weight: 628.8
‘&“CAS NO: 1155419-89-8 BI 224436
Purity: 98%
Appearance: White
Chemical Name: (S)-N-((2S,4S,5S)-5-(2-(2,6-dimethylphenoxy)acetamido)-4-hydroxy-1,6-diphenylhexan-2-yl)-3-methyl-2-(2-oxo-tetrahydropyrimidin-1(2H)-yl)butanamideP-glycoprotein inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.atsjournals.org/doi/full/10.1164/rccm.200712-1827OC

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Author: DNA_ Alkylatingdna