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Product Name: GDC-0879 | B-Raf inhibitor
Product Description: GDC0879 is highly selective, orally-bioavailable, oxime-containing pyrazole type inhibitor of B-Raf (V600E) kinase with a potency of 0.13 nM. [1] In a screening of a panel of kinases at 1 uM activity only RAF kinases were shown to have >90% inhibition,Medchemexpress.com
Chemical Formula: C19H18N4O2
Molecular Weight: 334.37
‘&“CAS NO: 1439399-58-2 CB-839
Purity: 98%
Appearance: White
Chemical Name: (E)-5-(1-(2-hydroxyethyl)-3-(pyridin-4-yl)-1H-pyrazol-4-yl)-2,3-dihydroinden-1-one oximeAntifolate inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.jbc.org/content/285/43/32695

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Author: DNA_ Alkylatingdna