Share this post on:

Product Name: PQ401 | IGF-1R inhibitor
Product Description: PQ401 is a diarylurea-based inhibitor of IGF-1R, inhibiting autophosphorylation in MCF-7 cells and the IGF-1R isolated kinase domain at IC50s of 12 uM and < 1 uM, respectively. In IGF-1R stimulated MCF-7 cells, PQ401 was more effective at an IC50 of 6 Web Site:Medchemexpress
Chemical Formula: C18H16ClN3O2
Molecular Weight: 341.79
‘&“CAS NO: 1038915-73-9 MK-4827 (tosylate)
Purity: 98%
Appearance: white
Chemical Name: N-(5-Chloro-2-methoxyphenyl)-N-(2-methylquinolin-4-yl)ureaToll-like Receptor (TLR) inhibitors
Solubility: Up to 50 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15210860

Share this post on:

Author: DNA_ Alkylatingdna