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Product Name: AMG-3969
Chemical Name: 2-[4-[(2S)-4-[(6-Amino-3-pyridinyl)sulfonyl]-2-(1-propyn-1-yl)-1-piperazinyl]phenyl]-1,1,1,3,3,3-hexafluoro-2-propanol)Theoretical AnalysisMetonChem Cat#: MC7030627
SMILES Code:
CAS NO: 465-11-2 Product: Atractylodin
Synonym: AMG3969; AMG 3969
Chemical Formula: C21H20F6N4O3SMolecular Weight: 522.46
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Sigma Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AMG-3969 is a potent glucokinase-glucokinase regulatory protein interaction (GK-GKRP) disruptor with an IC50 of 4 nM. AMG-3969 potently induced the dissociation of the GK-GKRP complex and promoted GK translocation in-vivo. In rodent model of diabetes, AMGPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22238366

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Author: DNA_ Alkylatingdna