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Product Name: AZD-3965
Chemical Name: (S)-5-(4-hydroxy-4-methylisoxazolidine-2-carbonyl)-1-isopropyl-3-methyl-6-((3-methyl-5-(trifluoromethyl)-1H-pyrazol-4-yl)methyl)thieno[2,3-d]pyrimidine-2,4(1H,3H)-dione
SMILES Code: O=C1N(C(C)C)C2=C(C(C(N3OC[[email protected]@](C)(O)C3)=O)=C(CC4=C(C(F)(F)F)NN=C4C)S2)C(N1C)=O
CAS NO: 7770-78-7 Product: Nedaplatin
Synonym: AZD3965; AZD 3965
Chemical Formula: C21H24F3N5O5SMolecular Weight: 515.506
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Carboxypeptidase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AZD3965 is a selective inhibitor of monocarboxylate transporter 1 (MCT1) with a binding affinity of 1.6 nM, is 6 fold selective over MCT2 and does not inhibit MCT4 at 10 μM. In vivo, AZD3965 is well tolerated and induces a dose and time dependent accumulaPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21316229

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Author: DNA_ Alkylatingdna