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Product Name: AZD3147
Chemical Name: 1-[4-[4-(1-cyclopropylsulfonylcyclopropyl)-6-[(3S)-3-methylmorpholin-4-yl]pyrimidin-2-yl]phenyl]-3-(2-hydroxyethyl)thiourea
SMILES Code: CC1COCCN1C2=NC(=NC(=C2)C3(CC3)S(=O)(=O)C4CC4)C5=CC=C(C=C5)NC(=S)NCCO
CAS NO: 1254053-43-4 Product: Y16
Synonym: AZD-3147; AZD 3147
Chemical Formula: C24H31N5O4S2Molecular Weight: 517.66
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).G-quadruplex inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AZD3147 is potent and selective dual mTORC1 and 2 inhibitor (IC50 = 1.5 nM). Exhibits >300-fold selectivity for mTOR over PI 3-kinase isoforms with physicochemical and pharmacokinetic properties suitable for development as a potential clinical candidatPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22149876

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Author: DNA_ Alkylatingdna