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Product Name: BDA-366
Chemical Name: 1-(((S)-3-(diethylamino)-2-hydroxypropyl)amino)-4-((((S)-oxiran-2-yl)methyl)amino)anthracene-9,10-dione
SMILES Code: CCN(CC)C[C@@H](O)CNC1=CC=C(NC[C@@H]2OC2)C3=C1C(C4=C(C3=O)C=CC=C4)=O
CAS NO: 249503-25-1 Product: Benzoylmesaconine
Synonym: BDA 366; BDA366
Chemical Formula: C24H29N3O4Molecular Weight: 423.513
Appearance: Solid powderMedchemexpress.com
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Somatostatin Receptor inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: BDA-366 is a BCL2-BH4 antagonist. BDA-366 suppresses human myeloma growth. BDA-366 induces robust apoptosis in MM cell lines and primary MM cells by inducing BCL2 conformational change. Delivery of BDA-366 substantially suppressed the growth of human MM xPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19209957

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Author: DNA_ Alkylatingdna

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Product Name: BDA-366
Chemical Name: 1-[[3-(Diethylamino)-2(S)-hydroxypropyl]amino]-4-[(2(S)-oxiranylmethyl)amino]-9,10-anthracenedione
SMILES Code: CCN(CC)C[C@@H](O)CNC1=CC=C(NC[C@@H]2OC2)C3=C1C(C4=C(C3=O)C=CC=C4)=O
CAS NO: 874758-58-4 Product: K-Ras G12C-IN-3
Synonym: BDA 366; BDA366
Chemical Formula: C24H29N3O4Molecular Weight: 423.5
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Pyruvate Dehydrogenase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: BDA-366 is a small-molecule Bcl2-BH4 domain antagonist, BDA-366, that binds BH4 with high affinity and selectivity. BDA-366-Bcl2 binding induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival moleculPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21618566

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Author: DNA_ Alkylatingdna