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Product Name: BMS-708163
Chemical Name: (R)-2-(4-chloro-N-(2-fluoro-4-(1,2,4-oxadiazol-3-yl)benzyl)phenylsulfonamido)-5,5,5-trifluoropentanamide
SMILES Code: O=C(N)[[email protected]](N(CC1=CC=C(C2=NOC=N2)C=C1F)S(=O)(C3=CC=C(Cl)C=C3)=O)CCC(F)(F)F
CAS NO: 127373-66-4 Product: Luminol (sodium salt)
Synonym: Avagacestat; BMS708163; BMS 708163
Chemical Formula: C20H17ClF4N4O4SMolecular Weight: 520.88
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Deubiquitinase inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: BMS-708163 (avagacestat) is an oral GSI designed for selective inhibition of Aβ synthesis currently in development for the treatment of mild to moderate and predementia AD. In addition to the desired effect on Aβ synthesis, GSIs affect Notch processing, wPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18046409

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Author: DNA_ Alkylatingdna