Share this post on:

Product Name: CFI-402257
Chemical Name: N-cyclopropyl-4-(7-((((1s,3s)-3-hydroxy-3-methylcyclobutyl)methyl)amino)-5-(pyridin-2-yloxy)pyrazolo[1,5-a]pyridin-3-yl)-2-methylbenzamide
SMILES Code: CC1=CC(C2=C(C=C(OC3=NC=CC=C3)C=C4NC[C@H]5C[C@](O)(C)C5)N4N=C2)=CC=C1C(NC6CC6)=O
CAS NO: 22204-24-6 Product: INT-747
Synonym: CFI 402257; CFI402257
Chemical Formula: C29H31N5O3Molecular Weight: 497.599
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Polo-like Kinase PLK) inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: CFI-402257 is a highly potent and selective TTK (threonine tyrosine kinase) Inhibitor ((TTK Ki = 0.1 nM) with potential anticancer activity. TTK is an essential chromosomal regulator and is overexpressed in aneuploid tumors. High TTK levels correlate withPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21747117

Share this post on:

Author: DNA_ Alkylatingdna