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Product Name: GNF-5837
Chemical Name: (Z)-1-(3-((3-((1H-pyrrol-2-yl)methylene)-2-oxoindolin-6-yl)amino)-4-methylphenyl)-3-(2-fluoro-5-(trifluoromethyl)phenyl)urea
SMILES Code: O=C(NC1=CC(C(F)(F)F)=CC=C1F)NC2=CC=C(C)C(NC3=CC(NC/4=O)=C(C=C3)C4=CC5=CC=CN5)=C2
CAS NO: 163847-77-6 Product: Formononetin
Synonym: GNF5837; GNF 5837
Chemical Formula: C28H21F4N5O2Molecular Weight: 535.492
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).DYRK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GNF-5837 is a potent, selective, and orally bioavailable pan-TRK inhibitor that inhibited tumor growth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. The properties of GNF-5837 make it a good tool for the elucidation of TRPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22559211

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Author: DNA_ Alkylatingdna