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Product Name: ML281
Chemical Name: N-[2-(3,4-Dihydro-3-oxo-2-quinoxalinyl)-4-(1-methylethyl)phenyl]-2-thiophenecarboxamide
SMILES Code: O=C(C1=CC=CS1)NC2=CC=C(C(C)C)C=C2C3=NC4=C(C=CC=C4)NC3=O
CAS NO: 1599432-08-2 Product: GSK-J1
Synonym: ML 281; ML-281
Chemical Formula: C22H19N3O2SMolecular Weight: 389.473
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Sirtuin inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. ML281 is a valuable addition to small-molecule pPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11585361

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Author: DNA_ Alkylatingdna