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Product Name: PFI-3
Chemical Name: (E)-1-(2-hydroxyphenyl)-3-((1R,4R)-5-(pyridin-2-yl)-2,5-diazabicyclo[2.2.1]heptan-2-yl)prop-2-en-1-one
SMILES Code: OC1=C(C(/C=C/N2[[email protected]](C3)CN(C4=NC=CC=C4)[[email protected]]3C2)=O)C=CC=C1
CAS NO: 504-24-5 Product: Eribulin
Synonym: PFI 3; PFI3
Chemical Formula: C19H19N3O2Molecular Weight: 321.38
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Naaddition)_HCO3- Cotransporter inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: PFI-3 is a potent and selective polybromo 1 and SMARCA4 inhibitor (Kd values are 48 and 89 nM respectively). PFI-3 is a potent, cell-permeable probe capable of displacing ectopically expressed, GFP-tagged SMARCA2-bromodomain from chromatin.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22884896

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Author: DNA_ Alkylatingdna