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Product Name: Pirarubicin
Chemical Name: (8S,10S)-10-(((2R,4S,5S,6S)-4-amino-6-methyl-5-(((S)-tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione
SMILES Code: O=C1C2=C(O)C(C[[email protected]](C(CO)=O)(O)C[[email protected]@H]3O[[email protected]]4C[[email protected]](N)[[email protected]](O[[email protected]]5CCCCO5)[[email protected]](C)O4)=C3C(O)=C2C(C6=C1C=CC=C6OC)=O
CAS NO: 82692-88-4 Product: Kauniolide
Synonym: Tepirubicin; Tetrahydropyranyl-Doxorubicin; THP-Adriamycin; THP-Doxorubicin
Chemical Formula: C32H37NO12Molecular Weight: 627.63
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Metabolism/Protease_Compound_Library inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin, which is an inhibitor of Topo II. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21767511

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Author: DNA_ Alkylatingdna