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Product Name: R-268712
Chemical Name: 4-[2-Fluoro-5-[3-(6-methyl-2-pyridinyl)-1H-pyrazol-4-yl]phenyl]-1H-pyrazole-1-ethanolTheoretical AnalysisMetonChem Cat#: MC7043018
SMILES Code:
CAS NO: 118525-35-2 Product: CBB1007 (hydrochloride)
Synonym: R268712; R 268712
Chemical Formula: C20H18FN5OMolecular Weight: 363.39
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).DNA-PK inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: R-268712 is a potent and selective inhibitor of the TGF-β type I receptor/ALK5 (IC50 = 2.5 nM), which exhibits ~5000-fold selectivity over p38 MAPK and suppresses development of renal fibrosis in a unilateral ureteral obstruction model.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17023575

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Author: DNA_ Alkylatingdna