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Product Name: SW044248
Chemical Name: 2-((5-ethyl-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio)-N-(2-methoxyphenyl)butanamide
SMILES Code: CCN1C2=CC=CC=C2C3=C1N=C(N=N3)SC(C(NC4=CC=CC=C4OC)=O)CC
CAS NO: 480-18-2 Product: BV6
Synonym: SW 044248; SW-044248
Chemical Formula: C22H23N5O2SMolecular Weight: 421.519
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).G-quadruplex inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: SW044248 is a potent and selective Topoisomerase I inhibitor. SW044248 killed approximately 15% of a panel of 74 NSCLC cell lines and was nontoxic to immortalized human bronchial cell lines. The acute transcriptional response to SW044248 in sensitive HCC4PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21690569

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Author: DNA_ Alkylatingdna