Product Name :
α-MSH, Free Acid
CAS NO. :
10466-28-1
Formula :
C77H108N20O20S
Molecular Weight::
1665.91
Target:
Melanocortin Receptor
Serial Number:
Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val
Short serial number :
Ac-SYSMEHFRWGKPV
Purity:
≥95%
Description :
α-MSH free acid (α-Melanocyte-Stimulating Hormone free acid) is an MC3R and MC4R agonist with EC50s of 0.16 nM and 5.6 nM, respectively. α-MSH free acid activates cAMP generation at MC3R and MC4R.
References:
[1]. Miwa H, et al. Structural determinants of the melanocortin peptides required for activation of melanocortin-3 and melanocortin-4 receptors. J Pharmacol Exp Ther. 1995;273(1):367-372.
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