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Product Name :
Hemokinin 1 (human)

CAS NO. :
491851-53-7

Formula :
C54H84N14O14S1

Molecular Weight::
1185.4

Target:
Neurokinin Receptor

Serial Number:
Thr-Gly-Lys-Ala-Ser-Gln-Phe-Phe-Gly-Leu-Met-NH2

Short serial number :
TGKASQFFGLM-NH2

Purity:
95%

Description :
Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia.Hemokinin 1 (human) is an endogenous substance P homolog and acts as a selective agonist at the tachykinin NK1 receptor (IC50 = 1.8, 370 and 480 nM for NK1, NK3 and NK2 receptors, respectively). It induces proliferation of B-cells in vitro and exhibits antihypertensive activity in vivo.

References:
[1].Cai-Yun Fu, et al. Hemokinin-1(4-11)-induced analgesia selectively up-regulates δ-opioid receptor expression in mice. PLoS One. [2].Francesca Bellucci, et al. Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. Br J Pharmacol. 2002 Jan;135(1):266-74.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna