Product Name :
α-Synuclein Binding Peptide
CAS NO. :
2243207-00-1
Formula :
C45H80O14N14
Molecular Weight::
1041.20
Target:
α-synuclein
Serial Number:
Ac-Lys-Asp-Gly-Ile-Val-Asn-Gly-Val-Lys-Ala-NH2
Short serial number :
Ac-KDGIVNGVKA-NH2
Purity:
95%
Description :
Cheruvara and coworkers conducted a single step selection followed by two rounds of competition selection protein-fragment complementation assay (PCA) in order to derive α-synuclein (α-syn) binders capable of inhibiting aggregation. They isolated a 10-residue peptide antagonist, corresponding to the sequence of α-synuclein binding peptide that potently inhibits α-synuclein aggregation and associated toxicity at 1:1 stoichiometry.
References:
[1].Intracellular screening of a peptide library to derive a potent peptide inhibitor of α-synuclein aggregation.
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