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Stry 258: 33193326. five. Simon MI, Strathmann MP, Gautam N Diversity of G proteins in signal transduction. Science 252: 802808. 6. Dizayee S, Kaestner S, Kuck F, Hein P, Klein C, et al. Correction: Galpha- and Galpha-Specific Regulation of Voltage-Dependent L-Type Calcium Channels in Felypressin web cardiomyocytes. PLoS One eight. doi:ten.1371/annotation/ 7be097c0-9075-41ae-91e9-d2209de952cc 7. Hippe HJ, Ludde M, Schnoes K, Novakovic A, Lutz S, et al. Competition for Gbetagamma dimers mediates a particular cross-talk in between stimulatory and inhibitory G protein alpha subunits in the adenylyl cyclase in cardiomyocytes. Naunyn-Schmiedeberg’s archives of pharmacology 386: 459469. eight. Albarran-Juarez J, Gilsbach R, Piekorz RP, Pexa K, Beetz N, et al. Modulation of alpha2-adrenoceptor functions by heterotrimeric Galphai protein isoforms. The Journal of pharmacology and experimental therapeutics 331: 35 44. 9. Nagata K, Ye C, Jain M, Milstone DS, Liao R, et al. Galpha but not Galpha is required for muscarinic inhibition of contractility and calcium currents in adult cardiomyocytes. Gracillin Circulation study 87: 903909. 10. Rudolph U, Finegold MJ, Rich SS, Harriman GR, Srinivasan Y, et al. Ulcerative colitis and adenocarcinoma of your colon in G alpha i2-deficient mice. Nature genetics ten: 143150. 11. Gohla A, Klement K, Piekorz RP, Pexa K, vom Dahl S, et al. An obligatory requirement for the heterotrimeric G protein Gi3 within the antiautophagic action of insulin within the liver. Proceedings of your National Academy of Sciences in the United states of america of America 104: 30033008. 12. Jin YZ, Thompson BD, Zhou ZY, Fu Y, Birnbaumer L, et al. Reciprocal function of Galphai2 and Galphai3 in graft-versus-host illness. European journal of immunology 38: 19881998. 13. Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, et al. Development of the mammalian axial skeleton requires signaling through the Galpha subfamily of heterotrimeric G proteins. Proceedings from the National Academy of Sciences from the Usa of America 109: 2136621371. 14. Ezan J, Lasvaux L, Gezer A, Novakovic A, May-Simera H, et al. Key cilium migration depends on G-protein signalling manage of subapical cytoskeleton. Nature cell biology 15: 11071115. ncb2819; doi:ten.1038/ ncb2819 15. Jantzen HM, Milstone DS, Gousset L, Conley PB, Mortensen RM Impaired activation of murine platelets lacking G alpha. The Journal of clinical investigation 108: 477483. 16. Wiege K, Le DD, Syed SN, Ali SR, Novakovic A, et al. Defective macrophage migration in Galphai2- but not Galphai3-deficient mice. Journal of immunology 189: 980987. 17. Wiege K, Ali SR, Gewecke B, Novakovic A, Konrad FM, et al. Galphai2 is definitely the essential Galphai protein in immune complex-induced lung disease. Journal of immunology 190: 324333. 18. Minetti GC, Feige JN, Bombard F, Heier A, Morvan F, et al. Galphai2 signaling is needed for skeletal muscle growth, regeneration, and satellite cell proliferation and differentiation. Molecular and cellular biology 34: 619630. MCB.00957-13; doi:ten.1128/MCB.00957-13 19. DeGeorge BR Jr, Gao E, Boucher M, Vinge LE, Martini JS, et al. Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic strain. Circulation 117: 13781387. 20. Waterson RE, Thompson CG, Mabe NW, Kaur K, Talbot JN, et al. Galpha-mediated protection from ischaemic injury is modulated by endogenous RGS proteins inside the mouse heart. Cardiovascular study 91: 4552. 21. Eckle T, Grenz A, Kohle.Stry 258: 33193326. five. Simon MI, Strathmann MP, Gautam N Diversity of G proteins in signal transduction. Science 252: 802808. six. Dizayee S, Kaestner S, Kuck F, Hein P, Klein C, et al. Correction: Galpha- and Galpha-Specific Regulation of Voltage-Dependent L-Type Calcium Channels in Cardiomyocytes. PLoS 1 8. doi:ten.1371/annotation/ 7be097c0-9075-41ae-91e9-d2209de952cc 7. Hippe HJ, Ludde M, Schnoes K, Novakovic A, Lutz S, et al. Competitors for Gbetagamma dimers mediates a distinct cross-talk in between stimulatory and inhibitory G protein alpha subunits from the adenylyl cyclase in cardiomyocytes. Naunyn-Schmiedeberg’s archives of pharmacology 386: 459469. 8. Albarran-Juarez J, Gilsbach R, Piekorz RP, Pexa K, Beetz N, et al. Modulation of alpha2-adrenoceptor functions by heterotrimeric Galphai protein isoforms. The Journal of pharmacology and experimental therapeutics 331: 35 44. 9. Nagata K, Ye C, Jain M, Milstone DS, Liao R, et al. Galpha but not Galpha is needed for muscarinic inhibition of contractility and calcium currents in adult cardiomyocytes. Circulation study 87: 903909. 10. Rudolph U, Finegold MJ, Rich SS, Harriman GR, Srinivasan Y, et al. Ulcerative colitis and adenocarcinoma from the colon in G alpha i2-deficient mice. Nature genetics ten: 143150. 11. Gohla A, Klement K, Piekorz RP, Pexa K, vom Dahl S, et al. An obligatory requirement for the heterotrimeric G protein Gi3 in the antiautophagic action of insulin in the liver. Proceedings in the National Academy of Sciences from the United states of America 104: 30033008. 12. Jin YZ, Thompson BD, Zhou ZY, Fu Y, Birnbaumer L, et al. Reciprocal function of Galphai2 and Galphai3 in graft-versus-host disease. European journal of immunology 38: 19881998. 13. Plummer NW, Spicher K, Malphurs J, Akiyama H, Abramowitz J, et al. Improvement from the mammalian axial skeleton calls for signaling by means of the Galpha subfamily of heterotrimeric G proteins. Proceedings in the National Academy of Sciences from the United states of america of America 109: 2136621371. 14. Ezan J, Lasvaux L, Gezer A, Novakovic A, May-Simera H, et al. Main cilium migration depends upon G-protein signalling manage of subapical cytoskeleton. Nature cell biology 15: 11071115. ncb2819; doi:ten.1038/ ncb2819 15. Jantzen HM, Milstone DS, Gousset L, Conley PB, Mortensen RM Impaired activation of murine platelets lacking G alpha. The Journal of clinical investigation 108: 477483. 16. Wiege K, Le DD, Syed SN, Ali SR, Novakovic A, et al. Defective macrophage migration in Galphai2- but not Galphai3-deficient mice. Journal of immunology 189: 980987. 17. Wiege K, Ali SR, Gewecke B, Novakovic A, Konrad FM, et al. Galphai2 may be the crucial Galphai protein in immune complex-induced lung disease. Journal of immunology 190: 324333. 18. Minetti GC, Feige JN, Bombard F, Heier A, Morvan F, et al. Galphai2 signaling is required for skeletal muscle development, regeneration, and satellite cell proliferation and differentiation. Molecular and cellular biology 34: 619630. MCB.00957-13; doi:ten.1128/MCB.00957-13 19. DeGeorge BR Jr, Gao E, Boucher M, Vinge LE, Martini JS, et al. Targeted inhibition of cardiomyocyte Gi signaling enhances susceptibility to apoptotic cell death in response to ischemic stress. Circulation 117: 13781387. 20. Waterson RE, Thompson CG, Mabe NW, Kaur K, Talbot JN, et al. Galpha-mediated protection from ischaemic injury is modulated by endogenous RGS proteins within the mouse heart. Cardiovascular investigation 91: 4552. 21. Eckle T, Grenz A, Kohle.

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