Are). Complication rate employing a duodenoscope was (pancreatitis; embolism) vs (pancreatitis; biliary leak) using SBE (P , Chisquare),with out mortality. The use of a duodenoscope permitted total sphincterotomy and each plastic and metallic stent placement,whereas the usage of SBE frequently necessary to combine sphincterotomy with extra sphincteroplasty ( mm) and only Fr plastic stent placement was probable due to the . mm operating channel diameter. However,SBE allowed easy access towards the papilla within the afferent limb and sphincteroplasty normally allowed buy RIP2 kinase inhibitor 1 direct cholangioscopy working with SBE. Indications had been bile duct stones (chronic pancreatitis (cholangitis (livertransplantation Conclusion: Therapeutic ERCP good results price is high in individuals with Billroth II gastrectomy working with either a standard duodenoscope or the SBE,with an acceptable and comparable complication price. The choice of endoscope may rely on the endoscopists knowledge,postoperative anatomy (gastrojejunostomy and length of afferent limb) and therapeutic indication (metallic stent placement and direct cholangioscopy). Disclosure of Interest: None declaredP POSTERCP PANCREATITIS (PEP) DOES ROUTINE USE OF RECTAL INDOMETHACIN Impact OUTCOMES A HIGHVOLUME SINGLECENTRE Knowledge In the UK F. Abid,M. T. Huggett,J. M. PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/23749492 Hutchinson,S. M. Everett,M. H. Davies,R. E. England Gastroenterology,Hepatology,Radiology,St James University Hospital,Leeds,Leeds,Uk Speak to E-mail Address: faisal.abidnhs.net Introduction: PostERCP pancreatitis (PEP) can be a widespread but potentially lifethreatening complication of ERCP with an incidence of as much as in unselected individuals in large international series. Numerous prospective trials have shown that administration of rectal indomethacin is effective in reducing the incidence of PEP in highrisk patients. We aimed to evaluate the price and severity of PEP in an unselected group throughout the pre and postindomethacin era at our hospital,which has one of many biggest ERCP practices in the UK. Aims Methods: A retrospective evaluation of a prospectivelycollected ERCP database in all adult individuals undergoing ERCP from January to December . In no rectal indomethacin was offered,while in all individuals recieved it. In only highrisk individuals recieved indomethacin. Thus,the unselected patient cohorts from (pre group) and (post group) have been compared. PEP was diagnosed and categorised into mild,moderate and serious in accordance with Cottons consensus guidelines. Results: individuals have been included. Of individuals inside the pre group, created pancreatitis, mild, moderate and severe with deaths. Of individuals inside the post group, developed PEP; ( mild, moderate and serious with death. There was no difference inside the general incidence of pancreatitis involving the post and pre groups [OR , p.],however the combined incidence of moderate and extreme PEP was drastically decrease in the post group [OR , p.]. There was no difference in haemorrhage prices in post vs pre group [OR , p.]. Conclusion: We observed that in our cohort of sufferers the unselected use of rectal indomethacin didn’t significantly minimize the incidence of PEP,nonetheless there was a important reduction in moderate to extreme PEP. This study for that reason suggests a valuable effect from the routine use of rectal indomethacin in unselected patients,constant with present European Society of Gastrointestinal Endoscopy (ESGE) suggestions. References . Kochar B,Akshintala VS,et al. Incidence,severity,and mortality of postERCP pancreatit.