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Methyl ester of Z-DEVD-FMK, a specific caspase-3 inhibitor. Z-D(OMe)E(OMe)VD(OMe)-FMK reduces vulnerability to the neuronal death that occurs in the aftermath of kainic acid-evoked status epilepticus (SE).

[1]. Using a small molecule inhibitor of peptide: N-glycanase to probe its role in glycoprotein turnover. [2]. Genetically encoded protease substrate based on lanthanide-binding peptide for time-gated fluorescence detection. [3]. Resveratrol protects DAergic PC12 cells from high glucose-induced oxidative stress and apoptosis: effect on p53 and GRP75 localization. [4]. Doxorubicin-induced activation of protein kinase D1 through caspase-mediated proteolytic cleavage: identification of two cleavage sites by microsequencing.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna