Caspase 8 Substrate 1f, fluorogenic | DNA_ Alkylatingdna-alkylating.com

Product Name :
Caspase 8 Substrate 1f, fluorogenic

CAS NO. :
211990-57-7

Formula :
C31H38O12N4F3

Molecular Weight::
715.65

Target:
Caspase

Serial Number:
Ac-Ile-Glu-Thr-Asp-AFC

Short serial number :
Ac-IETD-AFC

Purity:
95%

Description :
Ac-IETD-AFC is a fluorogenic substrate of caspase-8, caspase-3, caspase-10, and granzyme B.

References:
[1]. [1]Kazimierz Weglarczyk, et al. Caspase-8 activation precedes alterations of mitochondrial membrane potential during monocyte apoptosis induced by phagocytosis and killing of Staphylococcus aureus. Infect Immun. 2004 May;72(5):2590-7. [2]. Przemysław Reszka, et al. Synthesis, enzymatic evaluation, and docking studies of fluorogenic caspase 8 tetrapeptide substrates. ChemMedChem. 2010 Jan;5(1):103-17.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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