Product Name :
Melanocyte stimulating hormone release inhibiting factor
CAS NO. :
2002-44-0
Formula :
C13H24N4O3
Molecular Weight::
284.35
Target:
Dopamine Receptor
Serial Number:
Pro-Leu-Gly-NH2
Short serial number :
PLG-NH2
Purity:
95%
Description :
MIF-I, the C-terminal tripeptide of oxytocin, has been shown to be active in numerous behavioral tests and clinical situations.Oxytocin C-terminal tripeptide acetate, an inhibitor of melanocyte-stimulating hormone (MSH) release, blocks the release of α-MSH, increases brain dopamine levels, and antagonizes physiological and behavioral opioid effects in vivo.
References:
[1]. Peptides and hydrolysates from casein and soy protein modulate the release of vasoactive substances from human aortic endothelial cells. [2].Iso-lactam and reduced amide analogues of the peptidomimetic dopamine receptor modulator 3(R)-[(2(S)-pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide [3]. Prolyl-leucyl-glycinamide, cyclo(leucylglycine), and derivatives block development of physical dependence on morphine in mice [4]. A spectrophotometric assay of gamma-glutamylcysteine synthetase and glutathione synthetase in crude extracts from tissues and cultured mammalian cells
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