Product Name :
Lyn peptide inhibitor
CAS NO. :
4033-42-5
Formula :
C115H184O24N30
Molecular Weight::
2370.88
Target:
Src/Interleukin Related
Serial Number:
Stearoyl-Tyr-Gly-Tyr-Arg-Leu-Arg-Arg-Lys-Trp-Glu-Glu-Lys-Ile-Pro-Asn-Pro-NH2
Short serial number :
Stearoyl-YGYRLRRKWEEKIPNP-NH2
Purity:
95%
Description :
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of the Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. It blocks Lyn activation and inhibits the binding of Lyn tyrosine kinase to the βc subunit of IL-3/GM-CSF/IL-5 receptors. It can be used for the study of asthma, allergic, and other eosinophilic disorders.
References:
[1]. T Adachi, et al. The mapping of the Lyn kinase binding site of the common beta subunit of IL-3/granulocyte-macrophage colony-stimulating factor/IL-5 receptor. J Immunol. 1999 Feb 1;162(3):1496-501. [2]. T Adachi, et al. A novel Lyn-binding peptide inhibitor blocks eosinophil differentiation, survival, and airway eosinophilic inflammation. J Immunol. 1999 Jul 15;163(2):939-46.
Related websites: https://www.medchemexpress.com/antibodies.html
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