Product Name :
Kisspeptin-10Metastin(45-54), Human
CAS NO. :
374675-21-5
Formula :
C63H83N17O14
Molecular Weight::
1302.44
Target:
Kisspeptin Receptor
Serial Number:
Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH2
Short serial number :
YNWNSFGLRF-NH2
Purity:
95%
Description :
Kisspeptin-10, human is a potent vasoconstrictor and inhibitor of angiogenesis. Kisspeptin-10, human acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10-GPR54 system plays an important role in embryonic kidney development. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression.Kisspeptin-10, human TFA is a potent vasoconstrictor and inhibitor of angiogenesis, it acts as a tumor metastasis suppressor via its receptor GPR54. Kisspeptin-10/GPR54 signaling induces osteoblast differentiation via NFATc4-mediated BMP2 expression. Kisspeptin-10 (KP-10) and its receptor GPR54 are key components in the regulation of GnRH secretion in humans and other mammals. Kisspeptin-10 protein binds to GPR54. Activation of Kisspeptin-10 suppresses pulmonary human melanoma and Kisspeptin-10 is a metastasis suppressor in breast cancer cells.
References:
[1]. Kisspeptin-10 (KP-10) stimulates osteoblast differentiation through GPR54-mediated regulation of BMP2 expression and activation.
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