Product Name :
Goralatide
CAS NO. :
127103-11-1
Formula :
C20H33O9N5
Molecular Weight::
487.50
Target:
Kisspeptin Receptor
Serial Number:
Ac-Ser-Asp-Lys-Pro
Short serial number :
Ac-SDKP
Purity:
95%
Description :
N-Acetyl-Ser-Asp-Lys-Pro, an endogenous tetrapeptide secreted by bone marrow, is a specific substrate for the N-terminal site of ACE.Goralatide is a physiological regulator of hematopoiesis and inhibits the entry into the S-phase of murine and human hematopoietic stem cells. Ac-SDKP is a physiological substrate of angiotensin I- converting enzyme (ACE).
References:
[1].Renal protective effects of N-acetyl-Ser-Asp-Lys-Pro in deoxycorticosterone acetate-salt hypertensive mice. [2]. N-acetyl-Ser-Asp-Lys-Pro inhibits interleukin-1β-mediated matrix metalloproteinase activation in cardiac fibroblasts. [3]. The hemoregulatory peptide N-acetyl-Ser-Asp-Lys-Pro is a natural and specific substrate of the N-terminal active site of human angiotensin-converting enzyme.
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