Ac-KQLR-AFC | DNA_ Alkylatingdna-alkylating.com

Product Name :
Ac-KQLR-AFC

CAS NO. :
1802078-38-1

Formula :
C35H51O8N9F3

Molecular Weight::
782.83

Target:

Serial Number:
Ac-Lys-Gln-Leu-Arg-AFC

Short serial number :
Ac-KQLR-AFC

Purity:
95%

Description :
Hepsin, a membrane-anchored serine protease, is overexpressed in ovarian and prostate cancer and in renal cell carcinoma and thus can serve as prognostic marker. Ac-KQLR-AFC is the optimal substrate for human hepsin, as KQLR / VVNG corresponds to its cleavage site. Excitation at 395-400 nm, emission at 495-505 nm.

References:
[1]. Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers. [2]. Allosteric antibody inhibition of human hepsin protease.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
Related websites: https://www.medchemexpress.com/antibodies.html
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Author: DNA_ Alkylatingdna

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