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Ser/Thr Protease

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H-D-Phe-Phe-Arg-chloromethyl ketone is a potent, specific and irreversible inhibitor of glandular and plasma kallikreins.Kallikrein inhibitor which is even effective in preventing apolipoprotein B-100 proteolysis in dextran sulfate (DS)-precipitated human plasma low density lipoproteins (LDL). D-FFR-CMK also inhibits gingipain R.

[1].Platelets, circulating tissue factor, and fibrin colocalize in ex vivo thrombi: real-time fluorescence images of thrombus formation and propagation under defined flow conditions. [2].Studies on the effect of serine protease inhibitors on activated contact factors. Application in amidolytic assays for factor XIIa, plasma kallikrein and factor XIa.

Antibodies are immunoglobulins secreted by effector lymphoid B cells into the bloodstream. Antibodies consist of two light peptide chains and two heavy peptide chains that are linked to each other by disulfide bonds to form a “Y” shaped structure. Both tips of the “Y” structure contain binding sites for a specific antigen. Antibodies are commonly used in medical research, pharmacological research, laboratory research, and health and epidemiological research. They play an important role in hot research areas such as targeted drug development, in vitro diagnostic assays, characterization of signaling pathways, detection of protein expression levels, and identification of candidate biomarkers.
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Author: DNA_ Alkylatingdna