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Product Name: BIBW2992 (Afatinib) | EGFR, Her2 inhibitor
Product Description: BIBW2992 (Afatinib) is an orally-available, aminoquinazoline-acrylamide-based inhibitor with IC50 potency for EGFRwt, EGFR(L858R), EGFR(L858R/T790M), and HER2 at 0.5, 0.4, 10, and 14 nM, respectively. [1] Via its crotonamide functional group, BIBW2992 tarWeb Site:Medchemexpress
Chemical Formula: C24H25ClFN5O3
Molecular Weight: 485.94
‘&“CAS NO: 700874-71-1 LY2109761
Purity: 98%
Appearance: Off White
Chemical Name: (S,E)-N-(4-(3-chloro-4-fluorophenylamino)-7-(tetrahydrofuran-3-yloxy)quinazolin-6-yl)-4-(dimethylamino)but-2-enamideCannabinoid Receptor inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16945323

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Author: DNA_ Alkylatingdna