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Product Name: GDC-0810
Chemical Name: (E)-3-(4-((E)-2-(2-chloro-4-fluorophenyl)-1-(1H-indazol-5-yl)but-1-en-1-yl)phenyl)acrylic acid
SMILES Code: O=C(O)/C=C/C1=CC=C(C=C1)/C(C2=CC3=C(NN=C3)C=C2)=C(CC)C4=CC=C(C=C4Cl)F
CAS NO: 1781882-65-2 Product: SKF-86002
Synonym: GDC0810; GDC 0810; ARN810; ARN 810; ARN-810; RG6046; RG-6046; RG 6046; Brilanestrant
Chemical Formula: C26H20ClFN2O2Molecular Weight: 446.9064
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Nucleoside Antimetabolite_Analog inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: GDC-0810 (ARN-810, RG6046) is an orally bioavailable Selective Estrogen Receptor Degrader (SERD) that demonstrates robust activity in tamoxifen-resistant breast cancer xenografts. GDC-0810 functions by binding to the estrogen receptor, inducing a conformaPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20460491

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Author: DNA_ Alkylatingdna