Product Name: R788 (Fostamatinib disodium) | Orally active Syk inhibitor
Product Description: R788 is an orally-available, ATP-competitive, methylene phosphate prodrug of R406, which is a potent inhibitor of Syk (IC50 = 41 nM). [1] In a broad panel of receptor, ion channel, and enzyme binding assays, R406 was shown to inhibit adenosine A3 receptorWeb Site：Medchemexpress
Chemical Formula: C23H24FN6O9P.2Na
Molecular Weight: 624.42
‘&“CAS NO: 781649-09-0 MK-0974
Purity: 98%
Appearance: White
Chemical Name: 2H-Pyrido[3,2-b]-1,4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-4-[(phosphonooxy)methyl]-, sodium salt (1:2)MyD88 inhibitors
Solubility: Up to 100 mM in DMSO
Shipping Condition: The product is shipped in a glass vial at ambient temperature.
Storage Condition: For longer shelf life, store solid powder at 4oC desiccated, or store DMSO solution at -20oC.PubMed ID:http://www.futuremedicine.com/doi/abs/10.1517/14796694.1.3.315
