Share this post on:

Product Name: AG-120
Chemical Name: (2S)-N-(1-(2-chlorophenyl)-2-((3,3-difluorocyclobutyl)amino)-2-oxoethyl)-1-(4-cyanopyridin-2-yl)-N-(5-fluoropyridin-3-yl)-5-oxopyrrolidine-2-carboxamide
SMILES Code: O=C([[email protected]](CC1)N(C2=NC=CC(C#N)=C2)C1=O)N(C(C3=CC=CC=C3Cl)C(NC4CC(F)(F)C4)=O)C5=CC(F)=CN=C5
CAS NO: 82611-85-6 Product: 6-Maleimidohexanoic acid N-hydroxysuccinimide ester
Synonym: AG120; AG 120; Ivosidenib
Chemical Formula: C28H22ClF3N6O3Molecular Weight: 582.97
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Quinones inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: AG-120 is an orally available inhibitor of isocitrate dehydrogenase type 1 (IDH1), with potential antineoplastic activity. Upon administration, AG-120 specifically inhibits a mutated form of IDH1 in the cytoplasm, which inhibits the formation of the oncomPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22015772

Share this post on:

Author: DNA_ Alkylatingdna