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Product Name: APD668
Chemical Name: isopropyl 4-((1-(2-fluoro-4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)oxy)piperidine-1-carboxylate
SMILES Code: O=C(N1CCC(OC2=C3C(N(C4=CC=C(S(=O)(C)=O)C=C4F)N=C3)=NC=N2)CC1)OC(C)C
CAS NO: 3599-32-4 Product: AP1903
Synonym: APD-668; APD 668; JNJ28630368; JNJ-28630368; JNJ 28630368
Chemical Formula: C21H24FN5O5SMolecular Weight: 477.51
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).FXR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: APD668 (JNJ-28630368) is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively. ADP668 showed activity to reduce blood glucose and glycated hemoglobin (HbA1c) levels in Zucker Diabetic Fatty (ZDF) rats over several wPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11531262

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Author: DNA_ Alkylatingdna

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Product Name: APD668
Chemical Name: isopropyl 4-((1-(2-fluoro-4-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)oxy)piperidine-1-carboxylate
SMILES Code: O=C(N1CCC(OC2=C3C(N(C4=CC=C(S(=O)(C)=O)C=C4F)N=C3)=NC=N2)CC1)OC(C)C
CAS NO: 3599-32-4 Product: AP1903
Synonym: APD-668; APD 668; JNJ28630368; JNJ-28630368; JNJ 28630368
Chemical Formula: C21H24FN5O5SMolecular Weight: 477.51
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).FXR inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: APD668 (JNJ-28630368) is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively. ADP668 showed activity to reduce blood glucose and glycated hemoglobin (HbA1c) levels in Zucker Diabetic Fatty (ZDF) rats over several wPubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/11531262

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Author: DNA_ Alkylatingdna