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Product Name: BGB-283
Chemical Name: 5-(((1R,1aS,6bR)-1-(6-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)-1a,6b-dihydro-1H-cyclopropa[b]benzofuran-5-yl)oxy)-3,4-dihydro-1,8-naphthyridin-2(1H)-one
SMILES Code: [H][[email protected]@]1(C2=CC(OC3=C(CCC4=O)C(N4)=NC=C3)=CC=C2O[[email protected]]51[H])[[email protected]@H]5C6=NC7=CC=C(C=C7N6)C(F)(F)F
CAS NO: 6202-23-9 Product: Baclofen
Synonym: BGB 283; BGB283
Chemical Formula: C25H17F3N4O3Molecular Weight: 478.43
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).IAP inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: BGB-283 is a Novel potent and selective RAF Kinase and EGFR inhibitor. BGB-283-displays Potent Antitumor Activity in B-RAF Mutated Colorectal Cancers. In vitro, BGB-283 potently inhibits B-RAFV600E-activated ERK phosphorylation and cell proliferation.PubMed ID:http://www.aacrmeetingabstracts.org/cgi/content/meeting_abstract/2008/1_Annual_Meeting/2311

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Author: DNA_ Alkylatingdna