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Product Name: FG-4592
Chemical Name: (4-hydroxy-1-methyl-7-phenoxyisoquinoline-3-carbonyl)glycine
SMILES Code: O=C(O)CNC(C1=C(O)C2=C(C(C)=N1)C=C(OC3=CC=CC=C3)C=C2)=O
CAS NO: 136236-51-6 Product: Ademetionine
Synonym: Roxadustat; FG4592; FG 4592; ASP1517; ASP 1517; ASP-1517
Chemical Formula: C19H16N2O5Molecular Weight: 352.35
Appearance: Solid powderWeb Site:Medchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).COX inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: FG-4592 (Roxadustat) is an HIF α prolyl hydroxylase inhibitor in a cell-free assay. It stabilizes HIF-2 and induces EPO production and stimulates erythropoiesis. FG-4592 transiently and moderately increased endogenous erythropoietin and reduced hepcidin.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/10882398

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Author: DNA_ Alkylatingdna