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Product Name: Niraparib HCl
Chemical Name: (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrochloride
SMILES Code: O=C(C1=CC=CC2=CN(C3=CC=C([[email protected]]4CNCCC4)C=C3)N=C12)N.[H]Cl
CAS NO: 1429881-91-3 Product: FH1
Synonym: Niraparib hydrochloride; MK4827 HCl; MK 4827 HCl; MK4827 HCl
Chemical Formula: C19H21ClN4OMolecular Weight: 356.854
Appearance: Solid powderWeb Site click
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).p97 inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Niraparib(MK-4827) Hcl is a selective inhibitor of PARP1/PARP2 with IC50 of 3.8 nM/2.1 nM; with great activity in cancer cells with mutant BRCA-1 and BRCA-2; >330-fold selective against PARP3, V-PARP and Tank1.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19172579

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Author: DNA_ Alkylatingdna