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Product Name: Torin-1
Chemical Name: 1-(4-(4-propionylpiperazin-1-yl)-3-(trifluoromethyl)phenyl)-9-(quinolin-3-yl)benzo[h][1,6]naphthyridin-2(1H)-one
SMILES Code: O=C1N(C2=CC=C(N3CCN(C(CC)=O)CC3)C(C(F)(F)F)=C2)C4=C(C=NC5=CC=C(C6=CC7=CC=CC=C7N=C6)C=C54)C=C1
CAS NO: 667463-62-9 Product: LY2857785
Synonym: Torin1; Torin 1
Chemical Formula: C35H28F3N5O2Molecular Weight: 607.6372
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).IRE1 inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: Torin-1 is a potent and selective mTOR inhibitor. The apoptosis-inducing mTOR inhibitor Torin-1 hindered growth, motility, invasion, and survival of CoCSCs in vitro, and suppressed tumor growth in vivo with a concomitant reduction in vessel formation.PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/5955596

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Author: DNA_ Alkylatingdna