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Product Name: VTP-27999
Chemical Name: methyl N-[2-[(3-chlorophenyl)-[(3R)-1-[[(2S)-2-(methylamino)-3-[(3R)-oxan-3-yl]propyl]carbamoyl]piperidin-3-yl]methoxy]ethyl]carbamate
SMILES Code: CNC(CC1CCCOC1)CNC(=O)N2CCCC(C2)C(C3=CC(=CC=C3)Cl)OCCNC(=O)OC
CAS NO: 891025-25-5 Product: AGN 205728
Synonym: VTP27999; VTP 27999
Chemical Formula: C26H41ClN4O5Molecular Weight: 525.08
Appearance: Solid powderMedchemexpress
Purity: 98% (this data is for the first batch)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical. This product is stable enough for a few weeks during ordinary shipping and time spent in Customs.
Storage Condition: Dry, dark and at 0 8211; 4 C for short term (days to weeks) or -20 C for long term (months to years).Monocarboxylate Transporter inhibitors
Solubility: Soluble in DMSO, not in water
Background Description: VTP-27999 is a highly potent and selective renin inhibitor. VTP-27999 demonstrated excellent selectivity over related and unrelated off-targets, >15% oral bioavailability in three species, oral efficacy in a double transgenic rat model of hypertension,PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19383823

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Author: DNA_ Alkylatingdna